20/01/2017

Highlighting NGS Disease panels

https://www.newmarketscientific.com/ngs

Illumina compatible disease panels


Amplicon sequencing is based on ultra-deep sequencing of PCR products for analysing genetic variations and differences in gene expression. This approach allows researchers to focus interrogation on key regions of genomic interest using a simple workflow.

Amplicon panels allow researchers to sequence large numbers of targeted gene regions from selected samples for analysis of mutational hot spots within a subset of genes or detection of copy number variations (CNVs), well-defined gene fusions, SNPs or Indels. RNA panels are also possible to look at differences in RNA levels of genes of interest.

Using amplicon panels is an easily scalable, simple to use, fast, cost-effective approach which can be applied to a broad range of organisms and/or genes.

The NEXTflex Amplicon Panels include primers flanking the regions of interest, library prep reagents, and barcodes needed for construction of libraries compatible with Illumina sequencing platforms.

Illumina compatible disease panel sequencing kits
BRCA1 and BRCA2 amplicon panels (FFPE & non FFPE)