An effective anti-glucagon like peptide-2 receptor (GLP2R) antibody (Cat No: 24200).
GLP-2 is an emerging neurotransmitter involved in feeding control in the hypothalamus and brain stem, and has also been shown to regulate satiety through the endocrine system. Additionally, GLP2R agonists have been effective in the treatment of digestive diseases as well as diabetes.
To further understand GLP-2 activity, use of ImmunoStar's GLP2R antibody allows for highly specific staining of neurons in the hypothalamus, brain stem, pancreatic α-cells, enteroendocrine cells in the intestine, as well as enteric neurons, and vagal sensory neurons.
The rabbit antibody for Glucagon-like Protein Receptor is generated for acetyl 65-88 amide sequence targeting rat and human proteins, but not mouse.
Produced by Dr. Mark Brownfield, the peptide sequence encoding the rat GLP2R was retrieved from the NCBI protein database and evaluated using GeneRunner software to generate antigen candidates for antibody production.
This antibody demonstrates significant labeling of enteroendocrine cells in the intestinal epithelium, as well as cell bodies of vagal afferents in nodose ganglia of the parasympathetic nervous system.
Immunolabelling of Western blot reveals a band of approximately 66 kDa in human and rat tissue.
Further product details are available here:
GLP-2 is an emerging neurotransmitter involved in feeding control in the hypothalamus and brain stem, and has also been shown to regulate satiety through the endocrine system. Additionally, GLP2R agonists have been effective in the treatment of digestive diseases as well as diabetes.
To further understand GLP-2 activity, use of ImmunoStar's GLP2R antibody allows for highly specific staining of neurons in the hypothalamus, brain stem, pancreatic α-cells, enteroendocrine cells in the intestine, as well as enteric neurons, and vagal sensory neurons.
The rabbit antibody for Glucagon-like Protein Receptor is generated for acetyl 65-88 amide sequence targeting rat and human proteins, but not mouse.
Produced by Dr. Mark Brownfield, the peptide sequence encoding the rat GLP2R was retrieved from the NCBI protein database and evaluated using GeneRunner software to generate antigen candidates for antibody production.
This antibody demonstrates significant labeling of enteroendocrine cells in the intestinal epithelium, as well as cell bodies of vagal afferents in nodose ganglia of the parasympathetic nervous system.
Immunolabelling of Western blot reveals a band of approximately 66 kDa in human and rat tissue.
Further product details are available here:
